唇和舌鳞状细胞癌临床病理因素差异性分析

Clinical pathological difference between squamous cell carcinoma of l ip and tongue

目的 研究唇和舌鳞状细胞癌临床病理差异性。方法 用临床和病理参数对50例唇鳞状细胞癌和26例舌鳞状细胞癌进行对比分析。结果 唇和舌鳞状细胞癌的肿瘤大小、分化程度、病理核分裂数等无显著性差异，在浸润深度，毛细血管数等方面有统计学意义。浸润深度和病理核分裂数与复发转移有关。结论 当唇鳞状细胞癌浸润深度大于5.1 mm，舌鳞状细胞癌大于6.5mm时，易出现复发转移。唇鳞状细胞癌的病理核分裂数大于2个时，易出现复发转移，大于3个时，易出现颈淋巴结转移；而病理核分裂数与舌鳞状细胞癌的颈淋巴结转移无关，与复发转移有关，当其多于2个时易出现复发转移；机体对唇鳞状细胞癌免疫反应程度高。

Objective To study the clinical pathological differe nce between squamous cell carcinoma of lip and tongue. Methods fifty squamous cell carcinoma of lip was compared with 26 squamous cell carcinom a o f tongue, and the difference and the similarity were showed at the same time, Results There was no statistical difference in tumor size, diff erent iation, pathological karyokinesis between squamous cell carcinoma of lip and of tongue. There were statistical differences in tumor thickness and capill ary. Tumor thickness and pathological karyokinesis were related to recur and met astases. Conclusion It is easy to recur and metastases when tum or thickness is larger than 5.1mm and 6.5mm in squamous cell carcinoma of lip an d squamous cell carcinoma of tongue respectively. Secondly, It is easy to recur and metastases in squamous cell carcinoma of lip when the number of pathologica l karyokinesis is more than 2, and cervical lymph node metastases would happen w hen the number of pathological karyokinesis is more than 3. Thirdly, the number of pathological karyokinesis is not corresponded with lymph node metastases in s quamous cell carcinoma of tongue. But recurrent and metastases would take place when the number of pathological karyokinesis is more than 2.