胰腺癌基因诊断研究进展

ADVANCES IN GENETIC DIAGNOSIS OF PANCREATIC CANCER

目的 探讨对胰腺癌诊断有意义的基因指标。方法 复习国外有关胰腺癌基因诊断方面的文献。结果 K ras、p5 3、DPC4和端粒酶基因可用于胰腺癌临床诊断。结论 胰腺癌相关基因的检测可用于胰腺癌的早期诊断。

Objective To search for the significant gene indicators in the diagnosis of pancreatic cancer. Methods Literatures about genetic diagnosis of pancreatic cancer were collected and reviewed. Results K-ras, p53, DPC4 and telomerase genes were considered to play important roles in the diagnosis of pancreatic cancer. Conclusion Detection of the genes related to pancreatic cancer may be of helpful in early diagnosis of pancreatic cancer.