QT间期对RR间期变化的响应及HRV与QTV的关联性分析

QT Interval Adaption to RR Interval Changes and Correlation Analysis between Heart Rate Variability and QT Interval Variability

体表心电图作为无创和连续的监测手段,在心脏安全评测方面具有重要而不可替代的位置。心电图中的间期时间序列包含着重要信息,其中以反映心动周期的RR间期序列,以及以QT间期为代表的反映心室复极化时程的间期序列,在临床上最为基础,相关的研究具有更为重要的意义。文中从应用基础研究的角度,就QT间期对于RR间期变化的响应,以及心率变异性(HRV)和QT间期变异性(QTV)关联性分析,分别介绍了其分析方法和研究进展,并且展望了可能的应用前景。

As a noninvasive and continuous monitoring method, surface electrocardiogram is significant in evaluating cardiac safety. The time interval series extracted from surface electrocardiogran contain important information. The RR and QT interval series, representing the cardiac cycle and the duration of ventrieular repolarization, are with more research value. From the perspective of applied basic research, the methods and progress, concerning the QT interval adaption to RR interval changes and correlation analysis between heart rate variability （HRV） and QT interval variability （QTV）, were introduced here. And their potential applications were discussed as well.