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1型糖尿病胰岛功能保护的治疗前景 被引量:3

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摘要 1型糖尿病(T1DM)是一种由促炎性自身反应性T淋巴细胞介导的慢性自身免疫性疾病,经直接或问接的机制导致分泌胰岛素的胰岛B细胞受损,终生依赖外源性胰岛素。T1DM的患病率每20年翻一番,5岁以下的儿童尤甚,因而寻求T1DM的临床治疗方法意义重大。
出处 《中华糖尿病杂志》 CAS CSCD 2013年第2期68-72,共5页 CHINESE JOURNAL OF DIABETES MELLITUS
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  • 1Michels AW, Eisenbarth GS. Immune intervention in type 1 diabetes. Semiu Immunol,2011,23 :214-219.
  • 2von Herrath M. Diabetes: a virus-gene collaboration. Nature, 2009,459:518-519.
  • 3Vaarala O, Ilonen J, Ruohtula T, et al. Removal of bovine insulin from cow's milk formula and early initiation of beta-cell autoimmunity in the FINDIA pilot study. Arch Pediatr Adolesc Med,2012,166:608-614.
  • 4Knip M, Virtanen SM, Seppa K, et al. Dietary intervention in infancy and later signs of beta-cell autoimmunity. N Engl J Med, 2010,363 : 1900-1908.
  • 5Hummel S, Pfluger M, Hummel M, et al. Primary dietary intervention study to reduce the risk of islet autoimmunity in children at increased risk for type 1 diabetes: the BABYDIET study. Diabetes Care,2011,34:1301-1305.
  • 6Harris S. Can vitamin D supplementation in infancy prevent type 1 diabetes?. Nutr Rev,2002,60 : 118-121.
  • 7Stiller CR, Dupre J, Gent M, et al. Effects of cyclosporine immunosuppression in insulin - dependent diabetes mellitus of recent onset. Science, 1984,223 : 1362-1367.
  • 8Carel JC, Boitard C, Eisenbarth G, et al. Cyclosporine delays but does not prevent clinical onset in glucose intolerant pre-type 1 diabetic children. J Autoimmun,1996,9:739-745.
  • 9Sobel DO, Henzke A, Abbassi V. Cyelosporin and methotrexate therapy induces remission in type 1 diabetes mellitus. Acta Diabetol, 2010,47 : 243 -250.
  • 10Faustman DL, Wang L, Okubo Y, et al. Proof-of-concept, randomized, controlled clinical trial of Bacillus-Calmette-Guerin for treatment of long-term type 1 diabetes. PLoS One,2012,7: e41756.

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