急性期浆细胞性乳腺炎术后切口Ⅰ期愈合率影响因素观察

Analysis of influence factors on postoperative Ⅰ phase wound healing rate of plasmocytic acute mastitis

目的探讨术前联合使用抗菌药物治疗急性期浆细胞性乳腺炎的有效性,寻求提高此期患者术后伤口Ⅰ期愈合率的方法。方法回顾性分析中南大学湘雅医院2006年1月-2010年12月经病理确诊,临床表现为局部红肿热痛的急性期浆细胞性乳腺炎患者75例,按治疗方法不同分为治疗组(术前联合抗炎药物治疗)和对照组(单纯手术治疗),全部患者均采用手术治疗。随访两组患者在术后1月手术切口Ⅰ期愈合率,并进行比较。同时治疗组进行不同药物联合使用治疗效果的分析。结果治疗组Ⅰ期愈合率为62.7%,明显高于对照组(33.3%)(P=0.017)。治疗组中三个使用不同抗生素亚组间无明显差异(P=0.965)。结论术前联合使用抗菌药物可提高术后伤口Ⅰ期愈合率。

[Objective] To evaluate the treatment effect by combining with antibiotics before surgery and seek the method for improving the rate of postoperative plasmocytic acute mastitis of I phase wound healing. [ Methods ] A retrospective review was conducted for 75 patients with plasmocytic acute mastitis which were final diagnosed pathologically and the clinical manifestation of which were local flare and thermalgia from January 2006 to December 2010 in Xiangya hospital of Central South University. The cases were all under surgical treatment which divided into the treatment group combined with antibiotics before surgery and comparison group simple operated. Compare the I phase wound healing rate between two groups by follow-up one month after the surgery and make the subgroup anal- ysis in treatment group. [Results] I phase wound healing rate in treatment group is 62.7% which is significantly higher than comparison group with 33.3%（P =0.017）. I phase wound healing rate of three groups in the treatment group has no significant difference（P =0.965）. [Conclusion] The combination of antibiotics before surgery can improve postoperative plasmocytic acute mastitis of I phase wound healing rate.