颈动脉超声对冠心病的定量预测价值

Quantitative predictive value of carotid artery ultrasonography to coronary artery disease

目的探讨颈动脉超声对冠心病的定量预测价值。方法选取临床疑诊冠心病的住院病人76例,应用超声测定颈动脉内中膜厚度(IMT),并与冠脉造影结果显示的最大狭窄程度进行对比分析。结果颈动脉膨大处(BIF)-IMT≥1.0mm对冠心病的阳性预测值、阴性预测值分别为88.0%和46.2%;BIF-IMT诊断冠心病的ROC曲线下面积(AUC)为0.739,预测临界点为0.95mm。应用ROC曲线,BIF-IMT对狭窄>75%的最佳分界点为2.35mm,相应曲线下面积为0.704(P<0.01)。结论根据BIF-IMT的不同界值点,可对冠脉狭窄程度及判断是否需进行冠脉造影提供重要参考价值。

Objective To evaluate the quantitative predictive value of carotid artery ultrasonography to coronary artery disease. Methods The IMT of 76 patients were measured by ultrasound. The level of stenosis of coronary artery was measured by coronary angiography and the largest stenosis percentage was recorded. Finally, the IMT and the largest stenosis percentage were analyzed and contrasted. Results The carotid artery bifurcation IMT≥I. 0mm could predict CAD with positive prediction of 88.0%, negative prediction of 46.2 %. The area under ROC curve was 0. 739, The IMT was 0.95ram at peak point of the ROC curve. Depending on ROC curve, the IMT was 2.35ram at peak point of the curve for stenosis〉75%. The AUC was 0. 704（P〈0.01）. Conclusion The method of divided by different IMT can provide reference value fnr the level of stenosis and whether to need to take the CAG.