弥凝联合干床训练治疗小儿遗尿症87例临床分析

Primary nocturnal enuresis treated by desmopressin and dry bed training:analysis of 87 cases

目的:分析弥凝结合干床训练治疗小儿遗尿症(PNE)的疗效。方法:将87例确诊为PNE的患儿随机分为弥凝治疗组(51例)和中药治疗组(36例),弥凝治疗组采用弥凝(0.1 mg/d,睡前顿服,连服3个月)联合干床训练治疗;中药治疗组采用中药结合干床训练治疗,连服3个疗程。观察两组临床疗效及不良反应。结果:弥凝治疗组有效率高于中药治疗组(88%对比67%),比较差异有统计学意义(P<0.05)。弥凝治疗组复发率低于中药治疗组(36%对比50%),但两组比较差异无统计学意义(P>0.05)。结论:弥凝结合干床治疗PNE疗效好,不良反应少。

Objective： To explore the therapeutic effect of desmopressin and dry bed training in primary noc turnal enuresis. Method： Eightysever children with Primary Nocturnal Enuresis were randomly divided into twogroups. Desmopressin group （51 cases） was treated by desmoprsessin with dry bed training for three months; Chi nese medicine group （36 cases） was treated by Chinese medicine with dry bed training for three courses. Clinical efficacy and adverse effects were observed and compared. Result： The effective rate was 88% in the desmopressin group and 67% in the chinese medicine group with a significant difference between the two groups （ P 〈 0.05 ）. The reoccurrence rate was 36% in the desmopressin group and 50% in the chinese medicine group with a nosignifi cant difference between the two groups （ P 〉 0. 05 ）. Conclusion： Desmopressin is effective and convenient and less sideeffect in the treatment of PNE.