归芪通便颗粒成型工艺研究

Study on formation process of Guiqi Tongbian granules

目的探讨归芪通便颗粒的最佳成型工艺条件。方法以颗粒流动性、临界相对湿度为评价指标,筛选出处方中加入辅料的种类及最佳的成型工艺条件。结果确定最佳成型工艺条件为浸膏粉∶麦芽糊精∶微粉硅胶最佳比例是5∶3.5∶1.5,用95%乙醇溶液制粒,颗粒的临界相对湿度为74.8%,休止角为34.95°。结论为归芪通便颗粒成型工艺提供了可靠依据。

Objective To ascertain the best formation process of Guiqi Tongbian granules. Methods The formation process of Guiqi Tongbian granules was optimized by granular fluidity, critical relative humidity as evalua- tion indexes, screened out prescription to add accessories types and the best molding process conditions. Results The optimum molding process condition for extract powder ： malt dextrin ： micro powder silica gel best proportion was 5 ： 3.5 ： 1.5,95% ethanol was used as wetting agent, critical relative humidity was 74.8% ,repose angle was 34.950o Conclusion The test provides reliable basis for formation process of Guiqi Tongbian granules.