摘要
无碱参与的条件下,研究了Cu盐催化芳基硼酸与硫酚的偶联反应.通过反应溶剂、温度、铜盐、配体等条件的优化,结果表明在空气中,以1,10-菲啰啉-醋酸铜为催化剂,DMSO/H2O(V∶V=1∶1)作为溶剂,反应温度为60℃,以较高产率合成二芳基硫醚.
Baes-free Cu（II）-catalyzed coupling reaction of arylboronic acid and thiols was described. After optimization of reaction conditions, such as solvents, reaction temperatures, copper salts and ligands, the results show that some biarylsulfides were synthesized in good yields using 1,10-phenanthroline-Cu（OAc）2oH20 as catalyst, DMSO/-H20 （V ： V= 1 ： 1） as solvent, under air atmosphere at 60℃.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2013年第2期343-347,共5页
Chinese Journal of Organic Chemistry
基金
浙江省自然科学基金(No.Y407081)资助项目~~
关键词
偶联反应
硫酚
芳基硼酸
1
10-菲啰啉
醋酸铜
coupling reaction
thiol
arylboronic acid
1,10-phenanthroline
cupric acetate
