中医体质调理对高血压病血栓前状态的干预研究

Intervention Research of Control Scheme of TCM Body Constitution on the Pro-thrombotic State (PTS) of Hypertension

目的:运用中医体质防治方案对高血压病血栓前状态(pro-thrombotic state,PTS)进行早期干预,观察高血压病控制情况、患者生活质量、高血压血栓前状态分子标志物水平及心肌梗死与脑梗死发生率的影响,评价中医体质防治方案对高血压病血栓前状态干预的可行性。方法:体质干预组与西医基础治疗的对照组进行对比研究。结果:体质干预组血压控制情况体质干预组与对照组差异有统计学意义(P<0.05);体质干预组较对照组生活质量改善明显(P<0.05);体质干预组PTS分子标志物水平中vWF、GMP-140、11-DH-TXB2下降显著显,AT升高显著,与对照组比较差异有统计学意义(P<0.05);心肌梗死率及脑梗死率,差异有统计学意义(P<0.05)。结论:中医体质防治方案在高血压病血栓前状态的干预效果显著。

Objective The pro-thrombotic state （PTS） of hypertension was given to early intervention with con- trol scheme of TCM body constitution. And the feasibility of TCM body constitution control scheme on hypertension was evaluated to do intervention to pro-thrombotic state （PTS）. Methods： Treatment group was treated by early in- tervention with control scheme of TCM body constitution, and control group was treated by western medicine. The results were compared with. Results： There was signifi 〈 0. 05）. So was on the quality of life （ P 〈 0. 05 ）. cant difference between the two groups on blood pressure （P In treatment group vWF, GMP-140 and l l-DH-TXB2 de- creased markedly, but AT increased, and significant difference showed up between the two groups on them （P 〈0. 05 ）. The difference was also statistically significant between the two groups on the incidence rates of myocardial infarction and cerebral infarction （P 〈 0. 05 ）. Conclusion The effect of control scheme of TCM body constitution is good and reliable on the pro-thrombotic state （PTS） of hypertension..