包头市青少年尿样中铅、镉、汞、砷含量参比值的探讨

Determination of the Reference Value for Lead,Cadmium,Mercury, Arsenic Concentration in Adolescent Urine in Baotou City

目的了解包头市健康人群体内重金属元素的暴露水平,确定包头市青少年尿样中铅、镉、汞、砷含量的参比值。方法采集6～16岁青少年的晨尿样品,用ICP-MS测定其中的铅、镉、汞、砷含量,求其95%可信限的参考值范围。结果尿中铅、镉、汞、砷的检测数据呈偏正态分布,但经对数转换后符合正态分布且性别间差异无统计学意义(P>0.05)。结论根据本次调查结果初步确定包头市6～16岁青少年尿中重金属含量的参比值分别为铅<72.76μg/g,镉<10.51μg/g,汞<4.034μg/g和砷<242.6μg/g。

Objectives To survey the exposure levels of heavy metals in healthy youth people and determine the reference value for lead, cadmium, mercury, arsenic concentration in adolescent urine in Baotou city. Meth- ods The morning urine samples from adolescent of 6 - 16 age-bracket were collected and the content of lead, cadmium, mercury, arsenic was determined by ICP-MS. Reference value ranges were determined in 95% confi- dence limit according to the determination results. Results The test data of lead, cadmium, mercury, arsenic in urine samples showed a skewed normal distribution, but it was in keeping with normal distribution after logarithmic transformation. There was no significant difference between genders （P 〉 0.05）. Conclusions The preliminary determination result showed that the reference value for lead, cadmium, mercury, arsenic concentration in morning urine collected from adolescent of 6 - 16 age-bracket in Baotou city is less than 72.76, 10.51, 4.034, 242.6 μg/g, respectively.