卡前列甲酯栓对产后出血的影响

Effect of Methyl Carprost Suppository on Postpartum Haemorrhage

目的 :为提高预防产后出血的临床效果 ,寻找一种新的更为安全高效的药物。方法 :将正常足月妊娠产道分娩、非高危妊娠的 16 0例 ,随机分为两组 ,观察卡前列甲酯栓或缩宫素对产后 2h内出血量的影响。实验组 10 0例 ,于胎儿娩出后立刻将卡前列甲酯栓 1枚 (1mg)放入阴道 ;对照组 6 0例 ,胎儿娩出后立刻肌肉注射缩宫素 10U。结果 :实验组产后 2h内平均出血量较对照组减少 12 0 . 3ml (P<0 0 1 ) ,第三产程平均时间较对照组缩短 6 0 2min (P <0 0 1 )。结论 :卡前列甲酯栓具有比缩宫素更强的宫缩作用。

Objective: To find a new safer and more efficient medicine to improve the clinical effects of preventing postpartum haemorrhage.Methods: 160 normal women at term with birth canal parturition and non-highly-dangerous pregnancy were randomly divided into 2 groups:100 as study group and 60 as control group.In study group women took one Methyl Carprost suppository (1mg) after childbirth,and in control group women were intramuscularly injected with oxytocin for controls.Results: The postpartum haemorrhage amount in study group was 120.3ml(p<0.01)less than that in control group,and the average time of the third bearing process was shortened by 6.02 min(p<0.01).Conclusion: Methyl Carprost had more positive effects on uterus contraction than oxytocin. [