耐甲氧西林金黄色葡萄球菌感染患者的高危因素分析

ANALYSIS OF THE HIGH RISK FACTORS OF PATIENTS WITH METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS(MRSA) INFECTIONS IN HOSPITAL

目的分析在医院引起耐甲氧西林金黄色葡萄球菌(MRSA)感染的高危因素,探讨MRSA感染患者的临床对策。方法回顾性分析2008年7月～2012年6月医院的MRSA感染病例26例患者的年龄、住院天数、联合使用抗生素数量、抗菌素使用时间、术后白细胞数、白蛋白、血色素等资料作量化进行多因素回归分析。结果多种抗生素的联合使用和长时间抗菌药物是MRSA感染的高危因素(p<0.05)。结论临床应注意抗生素的合理使用,严格无菌技术操作和消毒隔离措施是预防MRSA感染的重要措施。

Objective To investigate the high risk factors of methicillin resistant Staphylococcus anreus （MRSA） infections in hospital and explore the clinical countermeasures for infected patients. Methods 26 MRSA infection cases were observed from July 2008 to June 2012 in our hospital. Derive the patient＇s age, length of stay, number of joint use of antibiotics, time of antibiotic use, postoperative white blood cell count, albumin, hemoglobin and other information for quantitative multivariate regression analysis. Results The joint use of a variety of antibiotics and prolonged antimicrobial drugs are risk factors for MRSA infection （p 〈 0.05）. Conclusion Should be noted that the rational clinical use of antibiotics, strict aseptic technique, disinfection and isolation measures are the important measures to prevent MRSA infections.