阻塞性睡眠呼吸暂停低通气综合征相关因素分析

Pathogenic factors of obstructive sleep apnea hypopnea syndrome

目的探讨阻塞性睡眠呼吸暂停低通气综合征（OSAHS）的相关因素。方法对我科2010年1月至2011年12月所有诊断为OSAHS的580例患者根据OSAHS的严重程度分为轻度组（180例）、中度组（290例）、重度组（110例），比较BMI、呼吸暂停低通气指数（AHI）和夜间最低血氧饱和度等指标。结果重度组SAHS患者呼吸暂停低通气指数、平均血氧饱和度、夜间最低血氧饱和度高于轻度及中度组，组间差异均有统计学意义[分别为（67±20）7欠／h比（15±4）、（29±2）次／h，（86±3）％比（93±1）、（91±2）％，（69±2）％比（85±1）、（91±3）％，均P〈0．05]。结论OSAHS的发病因素有很多，肥胖、高血压等均为OSAHS的危险因素。

Objective To observe pathogenic factors of obstructive sleep apnea hypopnea syndrome （OSAHS）. Methods Totally 580 cases of OSAHS in 2010 and 2011 were enrolled. According to the severity of the disease, 558 cases OSAHS patients were divided into mild group （180 cases）, moderate group （290 cases） and severe group （110 cases）. Body mass index, apnea-hypopnea index （AHI） and night time minimum pulse oximetry （SaO2 ） were compared. Results Apnea -hypopnea index, average oxygen saturation, the lowest oxygen saturation in the severe group were higher than those in the mild group and moderate group [ （67 ± 20 ）times/h vs （15 ± 4）, （29±2）times/h; （86 .3）% vs （93 ±1）%, （91 ±2）% ; （69 ±2）% vs （85 ± 1）%, （91 ±3）%, respectively, all P 〈 0. 05 ]. Conclusion There are many correlated pathogenic factors of OSAHS, among which age, sex, weight and NC are risk pathogenic factors.