CAPD患者容量超荷影响因素的初步探讨

Study on Various Factors of Capacity Overload in Patients with CAPD

目的:观察CAPD患者不同治疗阶段的血浆C反应蛋白(CRP)、血红蛋白(HGB)、纤维蛋白原(FIB)、脂蛋白a(Lipa)、白蛋白(ALB)、血肌酐(Scr)、尿素清除指数(KT/V)、24h尿量(U24h)、糖化血红蛋白水平(HbA1C)指标间关系,对影响CAPD患者容量超荷因素进行初步研究。方法:测定60例CAPD患者不同治疗阶段的血浆C反应蛋白(CRP)、血红蛋白(HGB)、纤维蛋白原(FIB)、脂蛋白a(Lipa)、白蛋白(ALB)、血肌酐(Scr)、尿素清除指数(KT/V)、24h尿量(U24h)、糖化血红蛋白水平(HbA1C),分析容量超荷组和对照组各指标间的差异。结果:不同监测指标在CAPD治疗6月、12个月、18个月,均有显著的变化,而且随着CAPD治疗,KT/V变化提示腹膜转运类型呈动态演变。结论:纠正血糖血脂代谢异常、控制微炎症的发生、纠正营养不良及降低血液粘滞度,才能避免或减少CAPD患者容量超荷的发生。

Objective ：To analyze the relationship of the blood plasma C -reactive protein（CLIP） ,hemoglobin（ HGB ） ,fibrinogen （ FTB ）, lipoprotein a （ Lipa）, albumin （ ALB ）, serum ercatinine （ Ser）, blood urea Clear index （ KT / V ）, 24h urine outpul（U24h） ,the level of glycosylated hemoglobin（HbA1C） in the the patients on CAPD in different treatment stage, and study the ,varicus factors of capacity overload in patients on CAPD. Methods：To determinate the level of plasma CRP, and HGP,, and FIB, and Lipa, and ALB, arid Scr, and KT/V, and U24h, and HbAI C in 60 patients on CAPD in different treatment stage,analysis the differences between capacity overload group and controlled group among the indexes. Results：The different monitoring indicators in June,12 month.s, 18 months,has a significant changes in CAPD treatment,but treated with CAPD, KT/V change prompts peritoneal transport type is dynamic evolution. Conclusion：Correct abnormal glucose and lipid metabolism, control micro - inflammation, correct malnutrition and reducing blood viscosity, in order to avoid or reduce the occurrenee of CAPD patients with capaeity overload.