依那普利联合硝苯地平在老年性高血压中的应用价值研究

The Research of the Application Value for the Combination of Enalapril and Nifedipine in Senile Hypertension

目的:探讨依那普利联合硝苯地平治疗老年性高血压的疗效及其应用价值。方法:将本科收治的318例老年高血压患者随机分成三组,分别为依那普利组(A组)、硝苯地平组(B组)、依那普利硝苯地平联用组(C组),每组各106例。比较三组患者用药前、用药后第1、2、4周收缩压和舒张压,统计4周后三种降压药疗法的疗效。结果:用药后,三组患者的血压都得到了有效控制,其中C组患者的收缩压和舒张压明显低于A组和B组;第4周,C组的降压疗效显著高于A组和B组。结论:依那普利与硝苯地平联合用药能更好地控制老年患者的血压,降压效果十分优越,具有极高的临床应用价值。

Objective： To evaluate the efficacy of the value for the combination of enalapril and nifedipine in the treatment of senile hypertension. Method： 318 cases of elderly patients with hypertension in our hospital were randomly divided into three groups, namely the enalapfil group （ A ）, the nifedipine group （ B ） and the combination enalapril nifedipine group group （ C ）, and 106 cars in each group. The systolic and diastolic blood pressure 1, 2 and 4 weeks before and after treatment were compared.The efficacy of three antihypertensive drugs after 4 weeks was taken for statistics.Result： After treatment, the blood pressure of the three groups of patients had been effectively controlled, and the systolic and diastolic blood pressure of the patients of group C was significantly＇lower in group A and group B.The antihypertensive efficacy of group C was significantly higher than in group A and B group at the fourth week.Conclusion： The combination of enalapril and nifedipine can better control the blood pressure of elderly patients, and the antihypertensive effect is very superior, and it is with a high clinical value.