高血压脑出血的病理改变及脑出血对周围组织的影响

Hypertensive Cerebral Hemorrhage Pathological Change and Impact on Surrounding Tissue of Cerebral Hemorrhage

目的探讨分析高血压脑出血的病理变化及对周围正常脑组织的影响。方法回顾性分析34例高血压脑出血患者的病理资料,总结、归纳高血压脑出血病灶及血肿周围组织的病理改变。结果 34例高血压脑出血患者,病理检查镜下见含铁血黄素颗粒20例,神经胶质细胞增生14例,尼氏小体16例,神经细胞核固缩胞浆消失10例,血管内皮增生6例,钙化灶16例,软化灶14例,点片状出血17例。结论高血压脑出血脑组织病变是长时间高血压导致的慢性病理改变,且于出血后早期即出现局部和全脑的病理生理变化。

Objective To investigate the analysis of hypertension cerebral hemorrhage pathological changes and to the surrounding normal brain tissue of rats. Methods a retrospective analysis of 34 cases of hypertensive cerebral hemorrhage patients with patho- logical data, summarizing, hypertensive cerebral hemorrhage foci and perihematomal tissue pathological changes. Results 34 cases of hypertensive cerebral hemorrhage patients seen under the microscope, pathological examination of hemosiderin granules in 20 cases, glial cell hyperplasia in 14 cases, Nissl bodies in 16 cases, nerve nuclei pyknosis cytoplasm disappeared in 10 cases, en- dothelial hyperplasia in 6 cases, calcification in 16 cases, softening lesions in 14 cases, a bit flaky bleeding 17 cases. Conclusion hypertension cerebral hemorrhage brain lesions are long time hypertension leads to chronic pathological changes, and bleeding af- ter appeared early local and whole＇brain pathological changes.