糖皮质激素降阶梯疗法治疗160例慢性湿疹的临床疗效分析

Clinical curative effect analysis of chronic eczema cured by Glucocorticoids drop step treatment

目的探讨糖皮质激素降阶梯疗法治疗慢性湿疹的临床治疗效果。方法随机抽取2010—2011年在该院治疗慢性湿疹的患者160例,随机分为干预组和对照组,其中对照组分为甲、乙、丙三组。对干预组采用糖皮质激素降阶梯疗法进行治疗。对对照组中甲、乙、丙三组分别采用复方丙酸氯倍他索软膏治疗、糠酸莫米松软膏和氟芬那酸丁酯软膏进行治疗。结果干预组中患者的治疗效果与甲组相当,并且效果较之于乙组、丙组有明显优势;干预组中患者的不良反明显低于甲组患者,较之于乙组、丙组不良反应无统计学意义。结论糖皮质激素降阶梯疗法对治疗慢性湿疹治疗效果好,并且不良反应少。

Objective Analysis of glucocorticoid effect of de-escalation therapy in treatment of chronic eczema. Methods 2010- 2011 randomly in 160 cases of chronic eczema treated in our hospital, were randomly assigned to intervention and control groups, which are divided into three groups a, b and c in the control group. De-escalation therapy with glucocorticoid used in the inter- vention group for treatment. In the control group a, b, c three group use clobetasol propionate with betamethasone ointment in treating and mometasone Furoate ointment and butyl fluoride mefenamic acid ointment for treatment. Results Therapeutic effect and a group of patients in the intervention group, and effects than in Group b, group c has a clear advantage; poor patients in the intervention group patients with anti-significantly lower than a group compared to the adverse reactions of Group b, group c was not statistically significant. Conclusion Glucocorticoid effect of de-escalation therapy in treatment of chronic eczema treated with good effect, and fewer adverse reactions.