多学科综合治疗晚期血吸虫病效果观察

Multi-disciplinary treatment for advanced schistosomiasis

目的探讨多学科综合治疗晚期血吸虫病的疗效。方法选择2010年1月至2011年12月接受多学科综合治疗的173例晚期血吸虫病患者(其中巨脾型患者75例,腹水型患者98例)和2007年1月至2009年12月接受单学科治疗的晚期血吸虫病患者193例(其中巨脾型84例,腹水型109例)为研究对象,比较不同治疗模式的临床疗效。结果与单学科治疗相比,多学科综合治疗巨脾型晚期血吸虫病的术前准备时间、住院时间缩短(P<0.01),手术时间缩短、术后并发症减少、住院费用降低(P<0.05),病人投诉下降(P>0.05);治疗腹水型晚期血吸虫病的治疗前时间、腹水消失时间缩短(P<0.01),住院时间缩短、治疗后并发症减少、住院费用降低、病人投诉下降(P<0.05)。结论多学科综合治疗晚期血吸虫病能提高疗效,减少并发症,并改善患者的生活质量。

Objective To assess the efficiency of multi-disciplinary treatment （MDT） for advanced schistosomiasis. Methods A total of 173 advanced schistosomiasis patients who received MDT were selected from January 2010 to December 2011. These patients included 75 splenomegaly cases and 98 ascites cases. Other 193 advanced schistosomiasis patients who received single-discipline treatment （SDT） from January 2007 to December 2009 were also selected, and of them 84 cases were splenomegaly and 109 were ascites. The clinical efficiencies of the two different treatments were analyzed and assessed. Results Compared to the SDT group, the splenomegaly cases treated by MDT showed a shorter pre-operative preparation time and less days in hospi- talization （both P 〈 0.01 ）, less operation duration, decreased post-operative complications, lower hospitalization costs （all P 〈 0.05）, and less patient complaints （P 〉 0.05）. The ascites cases treated by MDT, compared to the SDT group, had less pre-treat- ment time, shorter ascites-disappearing time （both P 〈 0.01 ）, and less hospitalization duration, decreased post-treatment complications, lower hospitalization costs and less patient complaints （all P 〈 0.05）. Conclusion MDT has a better efficiency in the treatment of advanced schistosomiasis, and it reduces the operation complications and improves the life quality of the patients.