降钙素原在急性冠脉综合征和心源性休克中的预测价值研究进展

The Research Progress of Procalcitonin Prognostic Value in Acute Coronary Syndrome and Cardiogenic Shock Patients

急性冠脉综合征是一种炎症性疾病,血清中的炎症标志物如白介素(IL)-6、IL-8和C反应蛋白在临床上已经用于评价冠状动脉疾病患者。降钙素原(PCT)是一种急性期炎症因子,被广泛认为是感染的标志物。但目前急性冠脉综合征和心源性休克患者PCT水平的研究较少,而且存在很大争议。本文对近几年来PCT在急性冠脉综合征和心源性休克中的预测价值及其动态学变化作一综述。

Inflammation plays a key role in atherosclerosis. Acute coronary syndrome （ACS） is an inflammatory dis- ease. The inflammatory markers in serum, such as intedeukin （IL） -6, IL- 8 and C -reactive protein （CRP） , are used to evaluate patients with coronary artery disease. Procaleitonin （PCT） is inflammatory factor in acute period and has been widely used as markers of infection. So far, data on serum PCT levels in patients with ACS and cardiogenic shock is scarce and contro- versial. This paper will review PCT prognostic value and dynamics in acute coronary syndrome and cardiogenic shock patients in details.