兰州市柯萨奇病毒、埃可病毒和EB病毒抗体检测分析

The distribution status of coxsackie virus,Echovirus and EB Virus by IgM antibody analysis in Lanzhou

目的:探讨兰州市患者柯萨奇病毒、埃可病毒和EB病毒感染的病原学分布现状,为防治工作提供资料。方法:应用ELISA法检测患者急性期血清中3种病毒(ECHO、COX、EBV)特异性IgM抗体,以了解病原学分布。结果:本研究共检测埃可病毒(ECHO)6412例,阳性143例(2.23%),柯萨奇病毒(COX)6435例,阳性218例(3.39%),EB病毒(EBV)6567例,阳性311例(4.74%)。其中COX和EBV感染女性明显高于男性(P<0.01)。在不同年龄组中,1岁～7岁两组ECHO感染明显高于其它年龄组(P<0.05)。大于1岁的四个年龄组COX、EBV感染显著高于另外两个年龄组(P<0.01)。在不同季节中,ECHO感染在夏季最高(P<0.01)。COX和EBV感染无明显季节性差异(P>0.05)。结论:三种病毒4岁～7岁组患者感染最高。ECHO病毒夏季感染明显高于其他季节。COX、EB病毒在女性患者中感染较高。

Objective：To investigate the etiology, distribution status of Coxsackie vinxs, Echovirus and EB virus in Lanzhou. Methods： The specific IgMs of ECHO, COX and EBV in patients in acute stage were detected bv ELISA. Results： One hundred and forty -three positives （2.23%） were found in 6412 cases of ECttO; Two hun- dred and eighteen positives （3.39%） were found in 6435 cases of COX; Three hundred and eleven positives （4.74%） were found in 6567 cases of EBV. The COX and EBV infections in female patients were higher than male patients （P 〈 0.01 ）. Among different age groups, ECHO infection rate was higher in patients of 1 -7 years oht than the patients of other ages （P 〈 O. 05 ） ; patients older than 1 years old with COX and EB wel~ more than the patients of other ages （P 〈0.01 ）. By seasons, patients of ECHO mostly happened in summer while there were no diffier- ences for the patients with COX and EB. Conclusion： COX, ECHO and EBV infections were mainly distributed in patients aged 4 ～ 7 years old, ECHO infection had the highest occurrence rate in summer, and female patients with COX and EB infections were more than male patients.