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依达拉奉治疗20例急性心肌梗死疗效观察 被引量:1

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摘要 目的:探讨依达拉奉在急性心肌梗死治疗中的作用。方法:将40例急性心肌梗死患者随机分为治疗组和对照组,两组基础治疗为静脉滴注奥扎格雷钠、疏血通,皮下注射低分子肝素钠(有ST段抬高心肌梗死给予静脉溶栓),口服拜阿司匹林、辛伐他汀、单硝酸异山梨酯片等药物。治疗组加用依达拉奉30 mg加0.9%氯化钠100 ml静脉滴注,2次/d,疗程2周。结果:治疗组总有效率90.0%,较对照组75.0%高。结论:依达拉奉能清除自由基,治疗急性心肌梗死疗效明确。
作者 王树录 殷慧
出处 《吉林医学》 CAS 2013年第5期859-860,共2页 Jilin Medical Journal
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  • 1周四芳,吴星恒.自由基与心肌缺血再灌注损伤[J].实用临床医学(江西),2005,6(7):155-156. 被引量:8
  • 2Tsujita K,Shimomura H,Kawano H,et al.Effects of edara-vone on reperfusion injury in patients with acute myocardial infarc-tion[J].Am J Cardiol,2004,94(4):481.
  • 3Yellon DM,Hausenloy DJ.Myocardial reperfusion injury[J].N Engl J Med,2007,13(11):357.

二级参考文献24

  • 1吴卫春,王胜利.心肌缺血预适应的基本机制[J].医学综述,2005,11(2):170-173. 被引量:5
  • 2Skyschally A,Schulz R,Gres P.Attenuation of ischemic preconditioning in pigs by scavenging of free oxyradicals with ascorbic acid[J].AJP-Heart,2003,284:698~703.
  • 3McPherson BC,Yao Z.Morphine mimics preconditioning via free radical signals and mitochondrial K(ATP)channels in myocytes[J].Circulation,2001,103:290.
  • 4Inserte J,Garcia-Dorado D,Ruiz-Meana M,et al.Ischemic preconditioning attenuates calpain-mediated degradation of structural proteins through a protein kinase A-dependent mechanism[J].Cardiovasc Res,2004,64(1):105~114.
  • 5Yang XM,Proctor JB,Cui L,et al.Multiple,brief coronary occlusions during early reperfusion protect rabbit hearts by targeting cell signaling pathways[J].J Am Coll Cardiol,2004,44(5):1 103~1 110.
  • 6Yusuf S,Dagenais G,Pogue J,et al.Vitamin E supplementation and cardiovascular events in high-risk patients.The Heart Outcomes Prevention Evaluation Study Investigators[J].N Engl J Med,2000,342(3):154~160.
  • 7McKevith B,Kelly C,Stanner S,et al.The Food Standards Agency's antioxidants in food programme-a summary[J].J Hum Nutr Diet, 2003,16(4):257~263.
  • 8Haramaki N,Stewart DB,Aggarwal S,et al.Networking antioxidants in the isolated rat heart are selectively depleted by ischemia-reperfusion.[J].Free Radic Biol Med,1998,25(3):329~339.
  • 9Ruiz Gines JA,Lopez Ongil S,Gonzalez Rubio M,et al.Reactive oxygen species induce proliferation of bovine aortic endothelial cells[J].J Cardiovasc Pharmacol,2000,35(1):109~113.
  • 10Lebuffe G,Schumacker PT,Shao ZH,et al.ROS and NO trigger early preconditioning: relationship to mitochondrial KATP channel[J].Am J Physiol Heart Circ Physiol,2003,284(1):299~308.

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