我院53例感染性心内膜炎病原菌分布及耐药性情况调查

Investigation on the Distribution and Its Drug Resistance of Pathogen Bacteria in 53 Patients with Infective Endocarditis in Our Hospital

目的：调查本院53例感染性心内膜炎病原菌分布及耐药性情况。方法：选取本院2009年6月~2011年12月的53例感染性心内膜炎患者为研究对象,将所有患者的病原菌检出情况及耐药性情况进行分析及比较。结果：53例患者共检出53株病原菌,革兰阳性菌比例明显高于革兰阴性菌及真菌,且对红霉素、氨苄西林及左氧氟沙星耐药性高于其他药物,P均〈0.05,有显著性差异。结论：感染性心内膜炎病原菌以革兰阳性菌为主,且其耐药性也有一定的特点,可为其治疗提供依据。

Objective：To investigate the situation of pathogens distribution and its drug resistance of 53 patients with infective endocarditis in our hospital.Methods：53 patients with infective endocarditis in our hospital from June 2009 to December 2011 were selected as research object,then the situation of pathogens distribution and its drug resistance of all the patients were analyzed and compared.Results：53 pathogens were detected from 53 patients,the rate of Gram-positive bacteria was higher than those of Gram-negative bacteria and fungus,and the drug resistance for the erythromycin,ampicillin and levofloxacin were all higher than other drug,all P0.05,there were all significant differences.Conclusion：The pathogens of patients with infective endocarditis is mainly Gram-positive bacteria,and its drug resistance has its characteristics,so it can provide evidence for the treatment.