CAI与PAI患者血清高密度脂蛋白胆固醇及亚组份水平的研究

A STUDY OF SERUM HIGH DENSITY LIPOPROTEIN CHOLESTEROL AND ITS SUBCLASS LEVELS IN CAI AND PAI PATIENTS

作者总结42例皮层动脉脑梗塞(CAI)和70例穿通动脉脑梗塞(PAI)与同龄对照组51例的脂质、高密度脂蛋白胆固醇(HDL-C)及亚组份含量的变化。结果显示,CAI男女TG水平、TC/HDL—C比值,女LDL-C/HDL-C比值显著高于PAI;CAI男女HDL-C、HDL_2-C水平显著低于PAI。CAI、PAI男女HDL-C显著低于对照组,LDL-C水平显著高于对照组。PAI伴高血压者显著多于CAI。结果提示:血清HDL—C、HDL_2—C水平降低,LDL—C升高都是CAI、PAI共同的危险因素,对CAI的危险性更大,而PAI主要致病因素可能是高血压。

Lipids,high density lipoprotein cholesterol and its subclass levels were studied in 42 patients with cortical artery infarclion(CAI),70 with perforating artery infarction(PAI) and 51 normal controls. The results showed that the TG level,TC/HDL-c ratio,LDL-c/HDL-c ratio(only female)were significantly higher and the HDL-c,HDL2-c levels were lower in CAI group than those in PAI group. The HDL-c and LDL-c levels in patients with PAI and CAI were significantly lower and higher than those in normal controls, respectively. The attack rate of hypertension in PAI patients was significantly higher than that in the CAI patients. These results suggested that the lower HDL-c,HDL2-C levels and the higher LDL-c level were common risk factors in CAI and PAI patients and more dangerous to PAI patients. The main dangerous factor of PAI may be hypertension.