摘要
目的分析病例和复习文献提高对原发性粒细胞肉瘤(PGS)的临床病理特征、诊断和治疗的认识。方法回顾性分析1例PGS患者的临床资料并复习相关文献。结果 PGS以局部孤立性肿物为首发表现,病理显示核仁小,髓过氧化物酶(MPO)阳性有重要诊断意义。结论 PGS由于临床少见,诊断主要依靠免疫组织化学,尤其是对于MPO阳性者,必要时可加做髓系相关抗原,明确治疗方法与急性髓系白血病相似。
Objective To improve understanding of the clinical and pathological features, diagnosis and treatment of primary granulocytic sarcoma（PGS） through analyzing cases and literature review. Methods 1 case of PGS was studied retrospectively of clinical characteristics,and related literatures were reviewed. Re- suits The initial presentation of PGS was local isolated tumor. The pathology showed that the nucleolus was small,myeloperoxidase（MPO）-positive had great diagnostic significance. Conclusion Immunohistochemis- try is the main diagnostic tool because the primary granulocytic sarcoma was rare. Especially when the MPO is positive, the myeloid-associated antigen can be added for diagnosis. Treatment of PGS is similar to that of a- cute myeloid leukemia.
出处
《医学综述》
2013年第4期765-766,共2页
Medical Recapitulate
关键词
粒细胞肉瘤
尤文肉瘤
诊断
治疗
Granulocytie sarcoma
Ewing sarcoma
Diagnosis
Treatment
