黑曲霉培养物急性毒性和微核实验评价

ACUTE POISON AND MICRO NUCLEOLUS ASSAYS OF ASPERGILLUS NIGER CULTURES

以小白鼠为试验对象 ,对黑曲霉培养物的急性毒性和遗传性毒性进行了研究。结果表明 :黑曲霉培养物的 LD5 0>1 0 g/kg;黑曲霉培养物组与正常饲料组所引起的小鼠骨髓细胞微核率无显著差异。因此初步认为黑曲霉培养物是一种比较安全的饲料原料。

WT5”,6BZ]Acute poison and inheritance poison of the Aspergillus niger cultures were determined on mice. The results showed that LD 50 was higher than 10 g/kg. There was no significant difference in the rate of micronuclei between Aspergillus niger cultures and normal feed. The results suggest that Aspergillus niger cultures may be safe to use on animals.