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幽门螺杆菌感染与动脉粥样硬化的关系研究

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摘要 目的探讨幽门螺杆菌(helicobacter pylori,HP)感染与动脉粥样硬化的相关性,为脑血管病的防治提供依据。方法选取2011年1—8月收治的急性脑梗死患者46例为脑梗死组,随机选择同期门诊体检中心的49例为对照组,比较两组HPIgG阳性率、动脉硬化指数(AI)和颈总动脉内膜中层厚度(IMT)差异。两组间计量资料比较使用独立样本t检验,计数资料的比较用χ2检验,使用Iogistic回归分析控制影响因素对检测指标的影响,P<0.05表示差异有统计学意义。结果脑梗死组患者HPIgG阳性率(89.13%)、AI(6.27±0.38)、IMT(2.78±0.35)显著高于对照组,差异均有统计学意义(均P<0.05)。结论 HP感染与动脉粥样硬化密切相关,可能是通过影响血脂代谢加重动脉粥样硬化的发生、发展,导致脑梗死的发生。
出处 《社区医学杂志》 2013年第4期40-41,共2页 Journal Of Community Medicine
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参考文献8

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