甘肃省朝觐人群高血压患病情况及与血细胞参数的关系

The prevalence of hypertension in pilgrims in Gansu and its relationship with blood cell parameters

目的了解甘肃省朝觐人群血压水平及高血压患病情况,并讨论高血压与血细胞参数间的相互关系。方法对2 221例朝觐体检者的血压及血细胞参数进行测定,并对其进行统计分析。结果 (1)该朝觐人群高血压检出率为60.69%(男性62.04%,女性59.04%),高血压前期检出率为26.07%(男性26.45%,女性25.60%)。男性舒张压、收缩压水平均高于女性(均有P<0.05),高血压检出率及高血压前期检出率在男女间差异均无统计学意义(均有P>0.05)。(2)高血压前期组/高血压组红细胞计数、红细胞压积、血红蛋白浓度、白细胞计数、中间细胞绝对值、中性粒细胞绝对值、血小板计数、血小板压积均高于正常组,平均红细胞体积则低于正常组(均有P<0.05);高血压组淋巴细胞绝对值、血小板分布宽度、平均血小板体积、大型血小板比率均高于正常组(均有P<0.05);各项血细胞指数在高血压前期组和高血压组间差异无统计学意义。结论甘肃省朝觐人群高血压检出率处于较高水平,高血压患者存在外周血细胞数目及形态学的改变,这可能与高血压的发病及急慢性并发症的发生有一定的联系,血细胞参数指标对高血压的防治具有一定的意义。

Objective To investigate the level of blood pressure and prevalence of hypertension in pilgrims in Gansu, and explore the relation between hypertension and blood cell parameters. Methods Data of blood pressure and cell parameters were obtained and measured from 2 221 pilgrims,and were analyzed statistically. Results （ 1 ）The detection rate of hypertension was 60. 69% （62. 04% for male, 59. 04% for female） in this pilgrims group, and the detection rate of prehypertension was 26.07% （26. 45% for male, 25. 60% for female） , and both systolic blood pressure and diastolic blood pressure in males＇ were higher than in females＇ （ all P 〈 0.05 ）. There was no statistically significant difference between male and female both in hypertension detection rate and prehypertension detection rate. （2） The red blood cell count, hematocrit, hemoglobin,white blood cell count, intermediate cell absolute value, meutrophils absolute value, platelet count, and platelet hematocrit in the prehypertension group and hypertension group were both higher than those in the normal group, and the mean corpuscular volume was lower than that in the normal group （ all P 〈 0. 05 ） ; the lymphocyte absolute value, platelet distribution width, mean platelet volume and large platelet ratio in the hypertension group were higher than those in the normal group（ all P 〈 0. 05 ） ; there was no statistically significant difference between the prehypertension group and hypertension group. Conclusions Hypertension was a salient problem for Gansu pilgrims. Our study showed that there were changes in peripheral blood cell from the patients with hypertension which may be related to the onset of acute and chronic complications in the hypertension progress. Blood cell parameters have some significance for the prevention and treatment of hypertension.