壬基酚对子代影响研究进展

Review on adverse effects of nonylphenol on offspring

壬基酚(NP)作为一种环境内分泌干扰物,是目前最常见的工业毒物和环境毒物。NP被排放到自然界中,对生态环境以及生物生存构成威胁。NP进入机体后会造成多种器官系统的损害。本文就当前NP对子代影响的研究进展进行总结,评估NP通过雌激素效应或毒性作用对子代生殖、免疫和神经等系统的损害,为限制这类化合物的使用提供依据。

Nonylphenol （NP） as an environmental endocrine disrupter （EEDs） is the most common industrial toxicant and environmental pollutant, which once discharged into natural world, it will pose a threat to ecological environment and biolog- ical survival. This review will summarize the research progress of the effects of NP on offspring of animals, and evaluates the im- pacts of NP on the reproductive, immune and nervous systems of rat offspring in order to provide a theoretic basis for confining the use of such kind of compounds.