经皮肝门静脉灌注化疗治疗肝癌

Through the chemotherapy of perfuding dermis liver portalvein to treat liver cancer

目的 观察经门静脉化疗对肝脏恶性肿瘤的有效性和安全性。方法 在B超定位下 ,经皮经肝穿刺入门静脉分枝内 ,注入卡铂 5 0 0mg、5 氟尿嘧啶 10 0 0mg ,阿霉素 5 0mg或者榄香烯乳 40 0～ 6 0 0mg,治疗后临床观察 1～ 2个月。结果 观察治疗前后的临床症状、体征。行B超及CT检查 ,肿瘤近期疗效明显 ,临床症状改善 ,肿瘤均有不同程度缩小 ,平均缩小 2 1% ,3例门静脉内癌栓病人 2例癌栓消失 ,不良反应较轻 ,均能耐受。结论 B超定位下 ,经皮肝门静脉介入治疗肝癌可明显改善临床症状 ,缩小肿瘤 ,是一种有效的治疗方法。

Objective To evaluate the effect and safety of portalvein chemotherapy against the liver malignance. Methods Under the localization of B ultrasound, through dermis and liver, paracente into the branches of portal vein, infude Carboplation 500mg, 5 Fluorouracil 1 000mg, Doxorubicin 50mg. or Elemene 400～600mg , every treatment needs clinical examination for 1～2months. Results To investigate the clinical symptom and signs of backward and forward of oncoma is very patent, the clinical symptom is improved, the oncoma is reduced to some degree, average coarctated about 21%.There are 3 cases of embolism of portal vein, two of whom disappeared, the uncomfortable reaction is relieved and can be borne. Conclusion Under the localization of B Ultrasound, through dermis and liver, intervention of portal vein, this kind of treatment can improve the clinical symptom and reduce oncoma, it's a kind of effective method of treament.