对比敏感度在糖尿病视网膜病变围激光期的检测意义

Significance of contrast sensitivity for diabetic retinopathy between the stage of pan retinal photocoagulation

目的:探讨对比敏感度(contrast sensitivity,CS)在糖尿病视网膜病变围激光期的检测意义。方法:所有糖尿病视网膜病变患者激光前后行CS和视力、眼底血管造影检查,并根据FFA分为非增殖期(25眼),增殖前期(27眼)和增殖期(35眼),采用532激光进行全视网膜光凝,一般每眼分3～4次完成,比较激光前后的视力和CS的变化。结果:激光后视力提高者22眼(35.48%),不变者34眼(54.84%),下降者6眼(9.68%)。光凝组两期激光前后,在低频、中频、高频时差异均有统计学意义(P<0.05),光凝组激光前与对照组比较,中频、高频均有统计学差异(P<0.05);激光后与对照组比较,在增殖前期时低中频无明显差异(P>0.05),增殖期各空间频率仍有统计学差异(P<0.05)。结论:CS能有效地评估糖尿病视网膜病变的进展变化,是糖尿病视网膜病变行全视网膜光凝的重要指征和有力证据。

· AIM： To explore the significance of contrast sensitivity （CS） for diabetic retinopathy （· DR） between the stage of pan retinal photocoagulation （PRP）. · METHODS： A total of 49 case （87 eyes） of DR was divided into three stages by the fundus fluorescein angiography （ FFA）, the first group was the stage of nonproliferative diabetic retinopathy （NPDR） （25 eyes）, the second group was the stage of pre-proliferative diabetic retinopathy（PPDR） （27 eyes）, the third group was the stage proliferative diabetic retinopathy （PDR） （35 eyes）. 532nm laser was used to have PRP for the PPDR and PDR groups, and retreated for 3-4 times, the CS and eye sight was performed around the stage of PRP. · RESULTS： After the laser, the eye sight was increased in 22 eyes, decreased in 6 eyes and unchanged in 34 eyes. There were significant differences around the stage of PRP in CS. The differences in middle and high frequency were significant （P〈0.05） between the control group and the laser group before PRP. After PRP, low and middle frequency had no significant difference （P〉0.05） between PPDR and control group, and each frequency had significant difference （P〈0.05） between PDR and control group. · CONCLUSION ： CS is an important method of evaluation of the changes the DR, and can become the guiding and proof of PRP in the treatment of DR.