氩激光格栅样光凝治疗BRVO致黄斑水肿的OCT观察

Observation of optical coherence tomography before and after argon laser grid photocoagulation for macular edema secondary to branch retinal vein occlusion

目的:应用光学相干断层扫描(optical coherence tomography,OCT)观测分析视网膜分支静脉阻塞(branch retinal vein occlusion,BRVO)致黄斑水肿(macular edema,ME)患者行氩激光光凝后视网膜水肿变化。方法:BRVO致视网膜水肿行氩(绿)激光光凝术,格栅状光凝12眼,光凝前及光凝后1,2,3,6mo分别行OCT图像检查。应用CIRRUS OCT自带程序行黄斑ETDRS区视网膜厚度分析,以中心凹1mm区域厚度及其变化值作统计学分析。结果:记录光凝后1,2,3,6mo黄斑中心1mm区厚度变化平均值分别为+7.3μm,-48.5μm,-79.0μm,-101.9μm。统计学分析视网膜厚度光凝前与光凝后2mo后两组间差异有统计学意义(P<0.05),光凝前与光凝后1mo差异无统计学意义。结论:OCT检测能准确定量定性测算黄斑区视网膜厚度变化,可观察氩激光光凝治疗BRVO致ME疗效,可作为光凝治疗疗效判断指标。

·AIM： To analyze the effect of argon laser photocoagulation in the treatment of macular edema related to branch retinal vein occlusion （BRVO） with optical coherence tomography （OCT）. · METHODS： Consecutive retrospective analysis of visual acuity （VA） and OCT from eyes treated with grid macular photocoagulation for BRVO-related macular edema were performed. Examed VA and central retinal thickness （CRT） before and after treating 1 month, 2, 3 and 6 months respectively were examined. Analysis of variance was used to compare pre- and post-treatment VA and CRT. · RESULTS： The macular retinal thickness was 352.3μm before photocoagulation. Within 6 months from symptom onset, 12 eyes had better visual acuity and less CRT than before photocoagulation. · CONCLUSION ： OCT is able to quantify the development and resolution of macular edema secondary to BRVO. It is a useful and non-injury tool to analyze the effect of photocoagulation.