原发性翼状胬肉与干眼关系的临床观察

Clinical observation about the relationship between primary pterygium and dry eye

目的:探讨原发性翼状胬肉与干眼的关系。方法:选择2011-08/2012-08住院行手术治疗的原发性单眼翼状胬肉患者50例,行回顾性分析,以胬肉眼为观察组,对侧眼为对照组,比较两组患者的眼部症状评分、泪液分泌试验(SchirmerⅠtest,SⅠt)、泪膜破裂时间(tear break-uptime,BUT)、眼表荧光素染色(fluorescent,FL)干眼评分。结果:观察组与对照组的SⅠt比较无统计学差异(P>0.05),但观察组BUT明显低于对照组(P<0.05),眼部症状、FL干眼症评分相比,观察组明显高于对照组(P<0.05)。结论:原发性翼状胬肉患者胬肉眼可同时患有干眼,可伴有明显的眼部干涩、视力下降、异物感等干眼症状,眼表泪膜的稳定性下降,并伴有眼表上皮的损害,翼状胬肉与干眼可同时共存,关系密切,但二者之间是否存在因果关系尚不明确。

· AIM： To observe the relationship between primary pterygium and dry eye. · METHODS： Totally 50 cases of primary pterygium from August 2011 to August 2012 in our hospital were retrospectively analyzed. Pterygium eyes composed the observing group and fellow eyes composed the control group. To compare the eye symptom score, Schirmer Ⅰ test, tear film break - up time （BUT） and oculo-surface fluorescent （FL） score of the two groups was evaluated. · RESULTS： There was nosignificant difference between observing and control group （ P〉 0.5）, but the tear film BUT of the observing group was obviously lower than the control group（P〈0.05）, the symptom and oculo- surface FL score were obviously higher of the observing group than the control group（P〈0.05）. · CONCLUSION： Patients who has primary pterygium may usually feel uncomfortable like eye drying, vision decreasing and foreign body sensation and so on. Primary pterygium may cut down the constancy of lacrimal film and cause the oculo- surface damage, but the causal relation between primary pterygium and dry eye is not clear at present.