原发性食管腺癌45例临床病理分析

The analysis of clinical pathology for 45 cases with primary esophageal adenocarcinoma

目的 :了解原发性食管腺癌的生物学特性 ,探讨合理的综合治疗措施。方法 :对 4 5例原发性食管腺癌患者的临床病理资料进行回顾性分析。结果 :其中食管单纯腺癌 32例 ,腺鳞癌 13例 ,1、3、5年生存率分别为 71 1%、53 1%和 4 7 0 %。结论 :因食管腺癌粘膜下浸润能力强 ,恶性程度高 ,有早期扩散和转移倾向 ,预后差 ,手术是其首选的主要治疗手段 ,以胸段食管全切、食管胃端侧颈部吻合术为宜 。

Objective:To explore the biological character of the primary esophageal adenocarcinoma and the reasonable complex treatment measure.Methods:45 cases with primary esophageal adenocarcinoma patients were treated by surgical procedure and confirmed by pathology,clinical pathology data for the patients with primary esophageal adenocarcinoma were analized retrospectively.Results:Total survival rates of 1,3 and 5year were 71.1%,37.8%and 17.8%,respectively. The prognosis was worse than that of the squamous cell carcinoma of the esophagus.Conclusions:surgical removal the lesion was the first therapeutic method, and it was necessary that the thoracic esophagus entirely resection and the endside esophagogastric anastomosis in cervical meanwhile removing regional lymph node. The complex treatment measure is under the investigation.