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扫描电镜下氟化物喂养大鼠耳蜗基底膜毛细胞形态

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摘要 目的:观察正常大鼠和氟化物喂养大鼠耳蜗基底膜毛细胞的形态,了解两者毛细胞的形态是否有差异性。方法:取正常大鼠和添加氟化物饲料喂养180 d的大鼠各2只,处死后取出耳蜗经制样后进行扫描电镜观察,比较两组大鼠耳蜗基底毛细胞差异。结果:正常组大鼠耳蜗基底膜毛细胞排成4排,内毛细胞排成1排,静纤毛呈"一"字型;外毛细胞排成3排,静纤毛呈"V"字型,毛细胞排列整齐、规则;实验组大鼠耳蜗基底膜外毛细胞出现排列不整齐、静纤毛形态不规则的现象,外毛细胞静纤毛呈柱状或不规则的团块状,静纤毛排列有缺失。结论:实验组大鼠耳蜗基底膜毛细胞有明显形态学改变,但大鼠听力是否受到损害还有待证实。
出处 《贵阳医学院学报》 CAS 2013年第1期76-78,共3页 Journal of Guiyang Medical College
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