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活性氧在神经病理性疼痛中的作用机制研究进展 被引量：2

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摘要 正常情况下体内抗氧化系统将活性氧维持在低水平的平衡状态,这种平衡一旦被打破,可影响细胞的结构和功能。近年来活性氧在神经病理性疼痛中的作用越来越受到重视;有研究表明:活性氧可以通过生成氧化应激产物、影响突触间神经递质的综合效能、调节蛋白激酶的活性、激活离子通道、影响胶质细胞活性、诱发神经元凋亡等方面发挥作用。本文对活性氧在神经病理性疼痛中的作用机制作一综述。
作者 吕虎 陈辉 熊源长
机构地区 第二军医大学附属长海医院麻醉科
出处 《中国疼痛医学杂志》 CAS CSCD 北大核心 2013年第3期130-133,138,共5页 Chinese Journal of Pain Medicine
基金 国家自然科学基金资助(81070894)
关键词 活性氧 痛觉过敏 信号通路
分类号 R741 [医药卫生—神经病学与精神病学]
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参考文献22

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共引文献2

同被引文献16

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中国疼痛医学杂志
2013年 第3期

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