缺血型烟雾病的临床特征及血管影像学诊断价值探讨

To study the clinical features and cerebrovascular imaging distinction of moyamoya disease

目的提高烟雾病的早期诊断率和早期干预治疗率。方法收集5年内确诊的11例缺血型烟雾病患者的临床特征、发病到确诊时间、血管检查结果及治疗方法的选择。结果儿童及青壮年发病率高,平均发病年龄为38.92±18.78。数字减影血管造影(DSA)检查率为91%;多层螺旋CT血管造影(CTA)检查率为36%;磁共振血管显影(MRA)检查率为27%,经颅多普勒超声(TCD)结果与DSA结果一致。36%患者行外科干预治疗。结论缺血型烟雾病临床症状复杂,容易漏诊或误诊;血管影像学检查是确诊和手术治疗的主要依据,TCD是最快最方便的筛选方法。

Objective To promote early diagnosis and interventional treatment rates of moyamoya disease. Methods 11 cases of ischemic moyamoya disease were collected in the past 5 years, the clinical features, time from symptom onset to diagnosis, blood vessels detection results and treatment options were recorded. Results The incidence in children and young adults were high,the average age was 38.92 ± 18.78;DSA examination rate was 91% , CTA examination rate was 36%, MRA examination rate was 27% ,the results of TCD was 100% corresponded with DSA ;36% cases received surgical intervention. Conclusion The clinical symptoms of ischemic moyamoya disease were complicated, easily missed or misdi- agnosed. Vascular imaging was the main basis for diagnosis and surgical treatment ,TCD was the quickest fast and most con- venient way method for of screening.