摘要
报告1例由左氧氟沙星诱发的大疱性类天疱疮。患者女,82岁。因发现躯干、四肢起红斑、水疱伴瘙痒7 d来诊。患者半年前曾有服用左氧氟沙星过敏史,该次服药后次日即引起红斑水疱性皮疹。组织病理检查提示表皮下水疱,疱内含有较多嗜酸性粒细胞;直接免疫荧光报告IgG、C3在表皮与真皮交界处呈线状沉积。结合皮疹特点诊断为大疱性类天疱疮。患者经糖皮质激素治疗,疗效满意。
A ease of bullous pemphigoid caused by levofloxacin is reported. An 82-year-old woman presented with crylhcma, blister and pruritus for 7 days. The patient had the same lesions after exposure to levofloxacin 6 months ago. The histopathology showed subepidermal blisters, filled with eosinophils. Direct immunofluorescence showed a linear baud of IgG and C3 alollg the basement membrane zone. The diagnosis of lcvofloxaein induced bullous pemphigoid was made. The patient got satisfactory result after corticosteroid therapy.
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
2013年第3期175-176,共2页
Journal of Clinical Dermatology