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六例遗传性易栓症的血栓发生与实验表型及基因型关联分析

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摘要 易栓症包括遗传性和获得性。获得性易栓症继发于手术创伤、制动、口服避孕药、母体免疫性疾病、恶性肿瘤等，遗传性易栓症主要是由蛋白c（Pc）、蛋白s（Ps）和抗凝血酶（AT）缺陷导致。AT缺陷的发病率为1／5000—1／500，病情较为严重。遗传性Pc缺陷为常染色体显性遗传病，
作者 曹雅楠 夏燕 王学锋 丁秋兰 许冠群 张利伟 戴菁 陆晔玲 奚晓东 王鸿利
机构地区 上海交通大学医学院附属瑞金医院、上海血液学研究所医学基因组学国家重点实验室
出处 《中华血液学杂志》 CAS CSCD 北大核心 2013年第3期256-258,共3页 Chinese Journal of Hematology
关键词 遗传性易栓症 实验表型 血栓发生 基因型 常染色体显性遗传病 获得性易栓症 口服避孕药 免疫性疾病
分类号 R5 [医药卫生—内科学]
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参考文献12

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二级参考文献8

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中华血液学杂志
2013年 第3期

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