摘要
肺炎链球菌导致的疾病已成为全球一个重要的公共卫生问题。疫苗开发及使用成为重要的预防策略,目前肺炎球菌疫苗主要有多糖疫苗和多糖蛋白结合疫苗二类。对肺炎链球菌病原学、流行病学、所致疾病、疫苗研发进展及疫苗使用情况进行了综述。
Pneumococcal disease is a major public health problem all over the world. Pneumococcal vaccine development and application become an important prevention strategy nowadays, which includes pneumococcal polysaccharide vaccine and pneumococcal polysaccharide-protein conjugate vaccine. Streptococcus pneumoniae etiology, epidemiology, diseases and pneumococcal vaccine research and application progress are summed up respectively in this review.
出处
《微生物学免疫学进展》
2013年第1期58-64,共7页
Progress In Microbiology and Immunology
基金
国家"863"计划疫苗研发关键技术及产品研发项目课题支持2012AA02A401
关键词
肺炎球菌
荚膜多糖
蛋白质结合疫苗
Pneumococcus
Capsular polysaccharide
Protein
Conjugate vaccine
