黄芪注射液对原发性肝癌患者肝动脉化疗栓塞后免疫及肝功能的影响

Effect of Huangqi Injection on Immune and Liver Function in Patients with Primary Hepatic Carcinoma after Hepatic Arterial Chemoembolization

目的:研究黄芪对原发性肝癌患者肝动脉化疗栓塞(HAE)后免疫及肝功能的影响。方法:60例原发性肝癌病人,行HAE后,随机分为两组,各30例。对照组HAE术后给予常规保肝支持治疗,治疗组在常规治疗基础上加用黄芪注射液20ml/d,疗程20天。在疗程结束前后观察两组病人T细胞亚群,红细胞免疫功能及肝功能的变化。结果:治疗组病人T细胞亚群、红细胞免疫功能及肝功能,治疗后有明正改善(P<0.01)而对照组病人上述指标改善不明显。结论:黄芪注射液对原发性肝癌病人的免疫及肝功能有明显改善作用,有增效减毒之功效。

Aim; To study the effect of Huangqi injection on immune and liver function in patients with primary hepatic carcinoma (PHC). Methods: 60 PHC patients after hepatic arterial chemoembolize (HAE). were randomly divided into two groups, there were observation group and control group. Each group had 30 patients. After HAE, observation group was added Huangqi injection 20ml/day for 20 days, besides routine therpy. On the other hand, control group was treated by routine therpy. Befor and after therpy, T lymphocyte subcolon (CD3, CD4, CD8), Red blood cell immune function (RBCCjbR, RBC-RICR)and liver function ALT Alb PT were recorded in all patients. All these parameters were expresed as X眘, and students t test were used when compared with normal. Results: In observation group, after Huangqi injection treatment, the parameter of CD3, CD4. RBC-C3bR, RBC-RICR. ALT, Alb PT were all improved re-markly (P<0. 01), but in control group most parameter which above mentioned were not improved remarkly (P> 0. 05), RBC-C3bR even aggravated (P<0. 01). Conclusion: Huangqi injection can remarkly improve the PHC patient's immune function and liver function after HAE therpy.