摘要
目的 :为中药复方 号抗癌转移的临床应用提供理论依据。方法 :小鼠子宫颈癌 U14 (腹水型 )接种于昆明小鼠左后肢爪垫皮下造成淋巴道转移模型 ,用形态学方法观察了各站淋巴结的转移情况。结果 :中药复方 号可抑制 U14 转移 ,大、中、小各剂量组及环磷酰胺的淋巴结转移抑制率分别为 :79.1%、6 6 .6 %、6 8.8%、4 3.3%。结论 :中药复方 号可一定程度抑制癌淋巴道转移。
Objective:To afford theory support for clinical practice,we observed inhibitory effect of Chinese Compound Recipe Ⅲ on animal model of lymphatic metastasis.Methods:Mouse Uterine Cervix Cancer No 14(ascitic type)was used as an experimental model for lymphatic metastasis.The tumor cells were transplanted subcutaneously into left footpats of Kunming mouse.Morphological assay was used to observe changes of lymph nodes and inoculated legs.Results:The CCRⅢ reduced metastasis of U 14 ,the inhibitory rates on lymphatic metastasis of large,medium,small dose and Cytoxan are 79 1%、66 6%、68 8%、43 3%respectively.Conclusion:The CRRⅢ could suppress metastasis of U 14 in some degree,it's mechanism worth deep study.
出处
《中国实验方剂学杂志》
CAS
2000年第5期20-22,共3页
Chinese Journal of Experimental Traditional Medical Formulae