米索前列醇用于产后出血的预防

Bleeding Prevention by Using Miso after Child Delivery

目的 :探讨米索前列醇预防产后出血的效果。方法 :选择1998年8月至1999年7月在我院住院分娩的300例单胎头位孕妇 ,随机分为米索前列醇组 ,催产素组 ,每组150例。米索组在胎儿娩出前 ,胎头着冠时给产妇直肠内置米索前列醇600ug。催产素组在胎儿娩出后产妇臀部肌注催产素20Iu。观察两组产后2h内出血量。结果 :产后2h平均出血量米索前列醇组明显低于催产素组 ,差异有极显著性 ;产后出血发生率米索前列醇组为3 3 % ,催产素组为10 7 % ,差异有显著性。结论 :直肠内置米索前列醇促子宫收缩作用比催产素强 ,能减少产后出血量 ,降低产后出血发生率 ,用药安全。

Objective: To explore the effect of preventing bleeding after birth-giving by using Miso. Methods: 300 cases of single baby women treated in our hospital from August, 1998 to July, 1999 were randomly divided into two groups… tested group and control group, with 150 cases every group. The women of tested group were given 600 ug Miso into rectum before their child delivery, and the women of control group were injected 20 IU Pitocin after their child delivery. Then we observed the bleeding amount of the two groups within two hours after the child delivery. Results: The bleeding amount of the tested group was much less than that of the control group and the difference was obvious. The bleeding rate of tested group was 3.3% while the control group remained 10.7%, from which the great difference could be seen. Conclusions: Using Miso can reduce the bleeding quantity and cut down the bleeding rate while more convenient and safety management could be got.