儿童神经元移行异常性脑回畸形的CT表现

CT Features of the Gyral Malformation of Neuronal Migrational Anomaly in Children

目的：分析神经元移行异常所引起的脑回发育畸形的 ＣＴ表现。材料和方法：回顾性分析 ２０例神经元移行异常脑回畸形的ＣＴ表现。结果：２０例中，无脑回畸形３例，非无脑回畸形１７例。前者表现为普遍性脑皮质均匀增厚，无脑沟形成或仅有少而浅的脑沟，脑表面光滑，脑回宽而扁平。后者表现为非普遍性脑皮质不均匀增厚，增厚皮质边缘高低不平，呈小波浪状或结节状隆起，增厚的皮质向深部折迭，形成皮质裂，部分病例白质内见胶质增生。结论：ＣＴ能够鉴别无脑回畸形和非无脑回畸形，为外科治疗由此而引起的难治性癫痫手术方案的选择提供依据。

Purpose: To analyse CT manifestations of gyral malformations of neuronal migrationl anomaly. Materials and Methods: CT manifestations of 20 patients with gyral malformation of neuronal migrational anomaly were retrospectively reviewed. Results: of the 20 patients, the lissencephalic type presented in 3 cases; the nonlissencephalic type was seen in 17 cases. The former showed that the cortex was an excessively uniform thickened without sulci, and brain surface was smooth (agyria), or only with a few and shallow sulci, and gyri were broad and flat (pachygyria). The latter CT findings were as follows: 1. A nongeneralized thickened, irregularly, bumpy cortex showed a wave form or a nodual bulge. 2. A deep infolding of thickened cortex. Gliosis in the white matter were seen in the nonlissencephalic type. Conclusion: CT was capable of differentiating lissencephaly from nonlissencephalic conical dysplasia and could provide valuable information for selecting surgical treatment planning of refractory epilepsy arising form these lesions.