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透明质酸衍生物在生物药品传递方面的研究进展 被引量：4

Advances of hyaluronic acid derivatives in biopharmaceuticals delivery
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摘要 目的综述透明质酸衍生物的制备及近年来在生物药品传递方面的研究进展。方法参考国内外相关文献32篇,进行相关信息的分析、归纳和总结。结果阐述通过化学修饰透明质酸制备衍生物的方法和在传递基因和蛋白质等生物药品方面的应用。结论透明质酸衍生物在药物传递方面将会有广阔的发展的前景。 Objective To summarize the preparation of hyaluronic acid derivatives and progress of its applica tions in biopharmaceuticals delivery recent years. Methods According to thirtytwo recent relevant litera tures, the preparation of hyaluronic acid derivatives and its development in genes and proteins delivery were summarized. Results The preparation methods of various derivatives by the chemical modification of hyalu ronic acid and the applications of hyaluronic acid derivatives in drug delivery were reviewed. Conclusions Hyaluronic acid derivatives in drug delivery field is promising.
作者 袁玉姣 蒋革 董爽
机构地区 大连大学生命科学与技术学院
出处 《沈阳药科大学学报》 CAS CSCD 北大核心 2013年第3期232-238,共7页 Journal of Shenyang Pharmaceutical University
基金 辽宁省教育厅项目(L2010030)
关键词 透明质酸衍生物 化学修饰 药物载体 生物药品 hyaluronic acid derivatives chemical modification drug carder biopharmaceuticals
分类号 R94 [医药卫生—药剂学]
  • 相关文献

参考文献32

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共引文献26

同被引文献69

  • 1闫雪霏,杨晔,尹登科.两亲性多糖自组装胶束给药系统研究进展[J].中国生化药物杂志,2014,34(4):174-178. 被引量：5
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引证文献4

二级引证文献10

沈阳药科大学学报
2013年 第3期

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