摘要
目的:评价目前市面上4个厂家5批次人参多糖注射液的质量。方法:从药物分析的角度,对人参多糖注射液进行常规检查,并测定其相对分子质量和单糖组成。结果:4个厂家的产品均符合相关质量标准和2010年版《中国药典》中的相关规定,但是相对分子质量分布和单糖组成差异很大。结论:建议提高人参多糖注射液的质量标准,保障安全用药。
Objective ： To evaluate injections of ginseng polysaccharide from 4 different manufacturers of 5 batches on the mar- ket. Method： Based on quality analysis, normal examinations were investigated, and monosaccharide composition and the molecular weight of polysaccharide in ginseng injections were performed. Result： Products from 4 different manufacturers were in line with the re- quirements of quality standard and Chinese Pharmacopeia （2010 edition）. But there were great differences in molecular weight and monosaccharide composition. Conclusion： It is suggested to enhance the quality standard to ensure the medication safety use.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2013年第5期683-686,共4页
China Journal of Chinese Materia Medica
基金
国家"重大新药创制"科技重大专项(2011ZX09401-097)
关键词
人参多糖注射剂
质量评价
相对分子质量
单糖组成
polysaccharide of ginseng injection
quality evaluation
relative molecular weight
monosaccharide composition
