高血压病靶器官损害与动态血压监测指标的相关性研究

A Correlative Research on Hypertension Target Organ Damage and Ambulatory Blood Pressure Monitoring Indi- cators

目的：探讨高血压病靶器官损害（TOD）与动态血压监测的收缩压（SBP）、舒张压（DBP）及平均动脉压（MBP）指标的相关性。方法：采用无创便携式动态血压监测仪对社区l24例高血压病患者进行24小时动态血压监测，根据MBP分为：I组，MBP〉I20mmHg，共108例；Ⅱ组，MBP〈120mmHg，共116例。每组再以脉压（PP）分为三个亚组：A组，PP〈60mmHg、B组，PP在60～79mmHg、C组，PP〉80mmHg。比较各组TOD发生率的差异。结果：I组的SBP、DBP、MBP均大于Ⅱ组（P〈O．05）；随SBP增加，TOD发生率逐步增加（P〈O．05）；而两组中相同亚组的TOD发生率无差异（P〉0．05）。结论：高血压病患者TOD与PP关系更为紧密。

Purpose： To explore the correlation between TOD and the indicators of SBP DBP and MBP. Method： To adopt noninva- sive portable ambulatory blood pressure monitor to undertake 24h monitoring for 124 hypertension patients. In accordance with MBP, they are divided into Group I including 108 cases and Group II including 116 eases, and the two groups are then divid- ed into three sub-groups respectively. The differences of TOD occurred in each group are compared. Result： SBP, DBP and MBP of Group I are all higher then those o Group II（P〈0.05）; the probability of TOD is increasing with the increasing of SBP（P〈0. 05）; the probability of TOD in sub-groups are the same（P〉0.05）. Conclusion： TOD of hypertension patients is more closely related to PP.