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白色念珠菌感染致早产儿右心室菌栓1例

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摘要 目的总结白色念珠菌感染致早产儿右心室菌栓的可能性及临床特征。方法回顾性分析南方医科大学珠江医院儿科中心收治的1例白色念珠菌感染致早产儿右心室菌栓的临床资料。患儿胎龄为32周,在当地医院经阴道产娩出。Apgar评分1min9分,5min、10min评分均10分,出生体质量1730g,羊水血性,脐带与胎盘无异常。患儿出生后逐渐出现呻吟、口吐白沫,三凹征明显,于出生10h予Ps猪肺磷脂注射液120mg注入气管内。胎龄评估35周。转入本院后再次气管内滴人PS猪肺磷脂注射液120mg。先后机械通气16d,入院第3天置中心静脉导管,部分胃肠外营养。于人院第38天用氟康唑经验性治疗1个月。结果患儿一直存在真菌性脓毒症,住院期间表现为间断低热和体质量增加缓慢,WBC〈5×10^9/L或〉15×10^9/L,血小板〈50×10^9/L,ALT基本正常。在入院第51天心脏彩超提示右心室腔异常条索状回声,经手术证实为白色念珠菌菌栓。结论早产儿侵袭性白色念珠菌可致右心室菌栓,应引起临床医师重视。
出处 《中华实用儿科临床杂志》 CAS CSCD 北大核心 2013年第2期151-152,共2页 Chinese Journal of Applied Clinical Pediatrics
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