繁木泻土汤治疗高脂血症的临床研究

Clinical research on Fanmu Xietu Tang for Treating Hyperlipemia

目的:探讨自拟繁木泻土汤治疗高脂血症的临床疗效。方法:150例高脂血症患者随机分为治疗组和对照组各75例。治疗组采用繁木泻土汤,1剂/d;对照组采用阿托伐他汀,20 mg,1次/d。疗程8周。观察两组血脂、血液流变指标。结果:治疗组总有效率81.3%,对照组为73.3%;两组治疗后血脂及载脂蛋白各指标较治疗前明显改善(P<0.05,P<0.01);治疗组除TC外,各指标改善均优于对照组(P<0.05,P<0.01);治疗后治疗组血液流变学各项指标均较治疗前显著降低,且均优于对照组(P<0.01)。结论:繁木泻土汤能有效调节高脂血症的血脂,改善患者血流状态,对高脂血症患者安全有效。

Objective： To study the clinical curative effect of Fanmu Xietu Tang （FXT） for treating hyperlipemia. Method： One hundred and fifty patients with hyperlipidemia were randomly divided into treatment group and control group （n=75 each）.The treatment group was given FXT, 1 agent daily.The control group was given atorvastatin, 20 mg daily.Treatment was lasted for 8 weeks.Blood lipids, blood rheological indexes were investigated. Result： Total effective rate in treatment group was 81.3%, and that was 71.3% in the controls.After treatment, blood lipids and apolipoprotein in two groups were obviously improved compared with those before treatment （P〈0.05, P〈0.01）.Except total cholesterol, other indexes in the treatment group were better than those in the controls （P〈0.05, P〈0.01）.After treatment the hemorheological indexes in the treatment group were improved compared with those before treatment, and better than those in control group （P〈0.01）. Conclusion： FXC could effectively control blood lipids in hyperlipidemia and improve blood flow condition.It is safe and effective.