子宫内膜癌309例临床及围手术期分析

Analysis of the clinical characteristics of 309 patients with endometrial carcinoma during the perioperative period

目的:分析子宫内膜癌患者临床及围手术期特征。方法:选取吉林大学第一医院手术治疗子宫内膜癌患者309例,将并存各种并发症的148例患者(合并症组)与同期无合并症的161例子宫内膜癌患者(对照组)的临床资料进行比较分析。结果:子宫内膜癌常见的合并症为高血压(97例)、糖尿病(52例),冠心病(12例)等,合并症组平均年龄(57.2±8.4)岁,对照组平均年龄(50.2±7.2)岁,合并症组的年龄明显高于对照组(P<0.01)。合并症发生情况与手术范围、肿瘤分期、分化程度和病理类型无关,而合并症者发生术后近期并发症的比例高于对照组(P<0.05)。结论:子宫内膜癌常合并高血压、糖尿病、冠心病等,合并症对治疗过程有一定的影响,治疗时要控制合并症,但合并症存在与否对预后无明显影响。

Objective： To explore the clinical characteristics of patients with endometrial carcinoma during the perioperative period. Methods： Three hundred and nine women with endometrial carcinoma who admitted to our hospital and underwent surgery were analyzed retrospectively. One hundred and forty - eight cases of endometrial carcinoma associated with medical disorders were chosen as complication group. The other 161 cases without medical disorders who admitted to our hospital during the same time were chosen as control. Results： Among the 148 patients with medical disorders, the ordinary disorders were hypertension in 97 patients, diabetes mellitus in 52 patients and coronary heart disease in 12 patients. Those patients with medical disorders were elder than the control （P 〈 0.01 ） . The medical disorders were independent of the operation scope, tumor stage, grade and pathological classification （ P 〉 0. 05 ） . The post operative complications ratio of patientswith medical disorders was higher than the control （ P 〈 0. 05） . Conclusion ： The endometrial carcinoma often associates with hypertension, diabetes mellitus, coronary heart disease and so on. The medical disorders may effect the therapy in a certain degree. Complications must be controlled during the therapy, but they don＇t affect the prognosis significantly.